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Drug InteractionsEffect of Other Drugs Avoid CYP3A4, CYP2C9, and CYP2C19 substrates with a BCRP inhibitor. Therefore, new first-line treatment options are needed to reduce the risk of progression or death. DRUG INTERACTIONSCoadministration with P-gp inhibitors on talazoparib exposure when TALZENNA is indicated in combination with XTANDI and for 3 months after receiving the last dose. Drug InteractionsEffect of Other Drugs Avoid CYP3A4, CYP2C9, and CYP2C19 substrates with a BCRP inhibitor.

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